Seroprevalence of Hepatitis B Virus Infection among people Living with HIV Attending at the Dangila Health Center, Northwest Ethiopia
Background: Hepatitis B virus (HBV) co-infection remains a significant cause of liver-related morbidity and mortality among people living with HIV/AIDS. Shared transmission routes increase the risk of co-infection, and HIV accelerates the progression of HBV-related liver disease despite widespread antiretroviral therapy (ART). However, there is limited up-to-date evidence on the seroprevalence and associated factors of HBV among HIV patients in the study area.
Objective: To assess the seroprevalence of HBV infection and identify associated risk factors among adults living with HIV attending at the Dangila Health Center, Northwest Ethiopia.
Methods: An institution-based cross-sectional study was conducted from June to August 2020 among 384 HIV-positive adults. Socio-demographic, behavioral, and clinical data were collected using a structured questionnaire and medical record review. Serum samples were tested for hepatitis B surface antigen (HBsAg) and anti-HCV antibodies using rapid test kits. Logistic regression analyses were performed to identify factors independently associated with HBV infection. A p-value <0.05 was considered statistically significant.
Results: The prevalence of HBV infection was 4.4% (17/384), indicating intermediate endemicity. No HCV infection was detected. In multivariate analysis, history of tooth extraction (AOR=3.17; 95% CI: 1.03–9.82), sexually transmitted diseases (AOR=3.53; 95% CI: 1.09–11.47), and multiple sexual partners (AOR=9.68; 95% CI: 2.45–38.24) were independently associated with HBV infection.
Conclusion: HBV co-infection remains a public health concern among HIV-positive individuals in this setting. Routine HBV screening, vaccination, and targeted behavioral interventions should be strengthened within HIV care programs.
Keywords
Authors
How to Cite
Download Citation
License
Copyright © 2025 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Similar Articles
- Dessie Tegegne, Aschalew Gelaw, Demeke Endalamaw, Getachew Ferede, Baye Gelaw, The association between ABO blood groups and norovirus infections among patients suffering from diarrheal disease in Northwest Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 14 No. 1 (2024)
- Getachew Ferede, Dengue Fever as an Emerging Health Concern in Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 9 No. 1 (2019)
- Amare Teshome Tefera, Nebiyou Bekele, Shegaye Shumet, Martha Solomon, Tigist Mulugeta, Dessie Abebaw, Prevalence and associated factors of periodontal disease in Ethiopia: systematic review and meta-analysis , Ethiopian Journal of Health and Biomedical Sciences: Vol. 15 No. 1 (2025)
- Meseret Mulu, Alem Getaneh, Worku Ferede, Aschalew Gelaw, Nasal Carriage Rate Of Methicillin Resistant Staphylococcus Aureus, Antimicrobial Susceptibility Pattern And Associated Risk Factors Among Pregnant Women At The University Of Gondar Comprehensive Specialized Hospital Northwest, Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 11 No. 1 (2021)
- Moges Tadesse, Takele Tadesse, Hardeep Rai Sharma, Mengsha Admassu, Prevalence of Needle-Stick Injuries and Associated Factors among Health Care Workers at Hawassa Town, South Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 2 No. 2 (2010)
- Belaynew Wasie, Yigzaw Kebede, Anwar Yibre, Nutritional Status of Adults Living With HIV/AIDS at the University of Gondar Referral Hospital, Northwest Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 3 No. I (2010)
- Tigist Alemu Kassa, Tobias Luck, Marion Michel, Samuel Kinde Birru, Steffi G. Riedel-Heller, Sexual and Reproductive Health Service Utilization among Young Disabled People in Ethiopia: a cross-sectional study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 13 No. 2 (2023)
- Mengistu Endris, Getasew Walle, Belaynew Wassie, Mulugeta Aemiro, Ligabaw Worku, Simon G/tsadik, Takele Teklu, Wubet Birhan, Jemal Ali, Bemnet Amare, Martha Alemayehu, Belay Anagaw, Aschalew Gelaw, Beyene Moges, Yeshambel Belyhun, Wossenseged Lemma, Meseret Delelegn, Prevalence of Intestinal Parasites and Associated Risk Factors among Students of Atse Fasil General Elementary School Azezo, Northwest Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 3 No. I (2010)
- Yohanness Sintayehu, Achenef Asmamaw, Tilahun Yemanu, Mehariw Birhan, Relapsing fever outbreak investigation in Beyeda district, North West Ethiopia, 2020,Case control study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 12 No. 2 (2022)
- Getahun Asres Aleme, Abebaw Gebeyehu, Clinical Improvement and Drug-Adverse Effects among Patients Taking Anti-Tuberculosis Drugs , Ethiopian Journal of Health and Biomedical Sciences: Vol. 2 No. 2 (2010)
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Gizeaddis Belay Mersha, Hailu Getachew, Yosef Getachew, Aimro Tadese, Tigist Birku, Michael Gete, Tazeb Molla, Alemayehu Abate, Belay Bezabih, Gene Mutations Conferring for Second-Line Drug-resistant Tuberculosis in Amhara Region: Eight-years Retrospective Study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 15 No. 1 (2025)
- Alemayehu Abate, Michael Getie, Gizeaddis Belay , Desalew Salew, Prevalence and Antimicrobial Resistance Patterns of Gram-Negative Bacteria at Amhara Public Health Institute, Northwest Ethiopia: A Six-Year Retrospective Study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 15 No. 2 (2025)