Seroprevalence of Hepatitis B Virus Infection among people Living with HIV Attending at the Dangila Health Center, Northwest Ethiopia
Background: Hepatitis B virus (HBV) co-infection remains a significant cause of liver-related morbidity and mortality among people living with HIV/AIDS. Shared transmission routes increase the risk of co-infection, and HIV accelerates the progression of HBV-related liver disease despite widespread antiretroviral therapy (ART). However, there is limited up-to-date evidence on the seroprevalence and associated factors of HBV among HIV patients in the study area.
Objective: To assess the seroprevalence of HBV infection and identify associated risk factors among adults living with HIV attending at the Dangila Health Center, Northwest Ethiopia.
Methods: An institution-based cross-sectional study was conducted from June to August 2020 among 384 HIV-positive adults. Socio-demographic, behavioral, and clinical data were collected using a structured questionnaire and medical record review. Serum samples were tested for hepatitis B surface antigen (HBsAg) and anti-HCV antibodies using rapid test kits. Logistic regression analyses were performed to identify factors independently associated with HBV infection. A p-value <0.05 was considered statistically significant.
Results: The prevalence of HBV infection was 4.4% (17/384), indicating intermediate endemicity. No HCV infection was detected. In multivariate analysis, history of tooth extraction (AOR=3.17; 95% CI: 1.03–9.82), sexually transmitted diseases (AOR=3.53; 95% CI: 1.09–11.47), and multiple sexual partners (AOR=9.68; 95% CI: 2.45–38.24) were independently associated with HBV infection.
Conclusion: HBV co-infection remains a public health concern among HIV-positive individuals in this setting. Routine HBV screening, vaccination, and targeted behavioral interventions should be strengthened within HIV care programs.
Keywords
Authors
How to Cite
Download Citation
License
Copyright © 2025 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Similar Articles
- Eden Bishaw Taye, Dawit Gebeyehu Mekonnen, Tibeb Zena Debele, Knowledge of Postpartum Women about Modern Contraceptive Methods and Attitudes towards its Utilization in Debre Tabor Town, Northwest Ethiopia: A Community-Based Cross-Sectional Study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 13 No. 1 (2023)
- Mohammed Oumer, Alemayehu Teklu , Edengenet Guday, Demiss Mulatu Geberu, Abebe Muche, Comparison of the Mean Length and Width of Anterior Fontanel among Newborns in Gondar City , Ethiopian Journal of Health and Biomedical Sciences: Vol. 11 No. 1 (2021)
- Asratie Guangul , Bahiru Tenaw , Sileshi Ayehualem, Abebe Muche, Radiographic Assessment of Cardiothoracic Ratio in Apparently Healthy Adults in Bahir Dar, Northwest Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 12 No. 2 (2022)
- Baye Gelaw, Bacteriophage Based Assay to Detect Mycobacteria in the Sputum of Tuberculosis Patients , Ethiopian Journal of Health and Biomedical Sciences: Vol. 6 No. 1 (2014)
- Aschalew Gelaw, Review on the epidemiology of astrovirus infections in East Africa and its public health significance , Ethiopian Journal of Health and Biomedical Sciences: Vol. 15 No. 1 (2025)
- Feseha Gebreselassie, Suleman Isa, Getahun Asres , Tuberculous Otitis Media in a 32 Year Old Ethiopian Woman , Ethiopian Journal of Health and Biomedical Sciences: Vol. 6 No. 1 (2014)
- Binyam Tilahun, Assegid Samuel, Alemayehu Teklu, Binyam Kefyalew, Adane Nigussie, Marta Feletto, Embedded Implementation Research on Compassionate and Respectful Care Services in the Ethiopian Health System , Ethiopian Journal of Health and Biomedical Sciences: Vol. 12 No. 1 (2022)
- Takele Tadesse, Assefa Getachew, Mengesha Admassu, Yigzaw Kebede, Tadesse Awoke, Tesfahun Melese, Solomon Amsalu, Shitaye Alemu, Gashaw Andargie, Belaynew Wassie, Yifokir Tefera, Sisay Yifru, Kassahun Alemu, Samuel G/ Selassie, Solomon Meseret, Demographic and Health Survey at Dabat District in Northwest Ethiopia: Report of the 2008 Baseline Survey , Ethiopian Journal of Health and Biomedical Sciences: Vol. 4 No. 1 (2011)
- Gashaw Messele, Yeshi Woldemedhin, Motuma Demissie, Kidanemariam Mamo, Aberra Geyid, Common Causes of Nosocomial Infections and Their Susceptibility Patterns in Two Hospitals in Addis Ababa , Ethiopian Journal of Health and Biomedical Sciences: Vol. 2 No. 1 (2009)
- Kassahun Desalegn, Takeshi Nishikawa, Afework Kassu, Andargachew Mulu, Gizachew Yismaw, Yeshambel Belyhun, Sisay Yifru, Fusao Ota, Level of Serum IgE during Atopy With and Without Intestinal Parasitic Infections in the University Of Gondar Teaching Hospital, Northwest Ethiopia , Ethiopian Journal of Health and Biomedical Sciences: Vol. 3 No. I (2010)
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Gizeaddis Belay Mersha, Hailu Getachew, Yosef Getachew, Aimro Tadese, Tigist Birku, Michael Gete, Tazeb Molla, Alemayehu Abate, Belay Bezabih, Gene Mutations Conferring for Second-Line Drug-resistant Tuberculosis in Amhara Region: Eight-years Retrospective Study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 15 No. 1 (2025)
- Alemayehu Abate, Michael Getie, Gizeaddis Belay , Desalew Salew, Prevalence and Antimicrobial Resistance Patterns of Gram-Negative Bacteria at Amhara Public Health Institute, Northwest Ethiopia: A Six-Year Retrospective Study , Ethiopian Journal of Health and Biomedical Sciences: Vol. 15 No. 2 (2025)